Lufenuron: Healing POTS, Anxiety & Introversion?

This is a two-part post so far. You can read the first installment here. Today the resolution of profoundly life-limiting symptoms, across a wide range of conditions, has me rethinking what dysbiosis might be. I hadn’t anticipated writing a new blog entry for Lufenuron yet, but some huge changes are happening daily. You can read about the first two weeks here.

Today is Day 15. As the candida is dwindling, symptoms of die-off returned, such as diarrhea. It makes sense, given the mix of Interfase Plus and Candizyme I am taking.

I woke with fairly loud tinnitus, my eyes were crusty with discharge (not my usual), and I just felt toxic. On the plus side, I had been feeling some pain while urinating these last few months but I’m now experiencing no prostatitis. Constipation is also no longer an issue. I’ve been having two bowel movements a day since Day 2 of Lufenuron, and my first today was a Bristol Stool Chart 5.5.

But as the day went on, I gathered steam, felt a bit better and went to a job interview. The drive over was relaxing, and I noticed even though it was hot outside, I had no heat intolerance. Tinnitus had virtually stopped by then, too.

I arrived early and parked, then noticed a bench on the sidewalk and sat down. Soon I was texting a friend, and as we chatted I realized I wasn’t the least bit sound-sensitive, which is unusual for my “post-Levaquin self“. In fact, I felt calm, relaxed, and was enjoying myself. Even a few days ago I would have felt exposed, hyper-aware of the noises around me, and been seeking the quiet of my car, with the windows rolled up. I’ve been suffering from this agoraphobia since i can remember, but I have also had candida since birth, too.

bench

Once in the lobby of the location where I was interviewing, there I sat on the couch, leafing through magazines. I had a huge epiphany. Reaching out for a photo-book, I was filled with a pleasant curiosity as I made my way through it. This is my old self! I remember family members remarking that my personality had changed, after I got blasted with antibiotics. This felt like that happy-go-lucky, engaging fellow returning.

The interview went really well. I felt relaxed, invested in conversation, transparent, not feeling the need to sell myself, just in the moment. Driving home I was upbeat and carefree. I rolled the windows down, feeling the blast of air on my skin. No sound sensitivity, and the fresh air felt great. I sensed how stale my car was (nose working now!), just because I’ve been leaving windows up constantly to avoid noise. Yes, my whole environment will need to detox with me.

Back at my house, I leaned down to the floor and adjusted a dimmer on a light, but my heart wasn’t pounding, and I didn’t feel like I was going to keel over. CFS has been a problem for the last 5 years, and it’s definitely been improving over the last week or so, but this evening I realized POTS symptoms have been disappearing, too. I really don’t have orthostatic intolerance anymore! And as I walk around the house my whole body feels lighter, stronger.

With improved bowel transport, even SIBO might be healing, and this new found energy puts some validity in that hunch, given how tired I get when upper gut fermentation is a problem. Perhaps candida has an adaptive mechanism, disrupting the migrating motor complex so it can consume more of our food. I’ve noticed GERD is also no longer a problem, which is likely tied to this same issue of decreased gut motility. I have a very happy colon now, and am hoping a lack of fungal overgrowth could heal my ulcerative colitis for good. Fingers crossed.

The wide range of improvements is impressive. I have to wonder, how many of us with POTS or SIBO are really just experiencing the neurological impairment caused by candida flourishing in our bodies, and its endlessly dumping of 79 toxins into our bloodstream? How much of being “floxed” (poisoned by fluoroquinolone antibiotics) relates to fungal overgrowth? And how many of us who became introverted, or prone to anxiety, after this gut flora damage — are we experiencing the same toxicity?

Day 15 of Lufenuron and yes, I feel pretty good.

I should add my point is not to recommend the use of Lufenuron, but rather, I think we need to pay close attention to fungal overgrowth, and relentlessly rid the body of candida however we can. In my case it appears to be making a huge difference.

UPDATE: I tried Lufenuron three times, and while the first dose provided incredible relief, when I took it again one month later it was only half as effective as it had initially been, and by the third dose, another month after that, it barely had an impact on my fungal overgrowth at all. This was despite mixing it with herbals.

Luckily I learned something valuable from the experiment: it seemed my immune system was the problem, so I began looking for something that could boost my body’s innate ability to fight candida. That led me to iodine, and a potential connection between fluorquinolone antibiotics, like Cipro and Levaquin, and hypothyroidism. Here’s the first installment of my iodine protocol. You’ll find the second article here. So far the results have been really encouraging, and unlike Lufenuron, iodine is both inexpensive and subject to much greater testing in humans.

If you enjoy this blog, you can support my work by buying things you need via this amazon portal HERE, or by purchasing any product linked in articles. It costs you nothing extra, and helps me continue writing. Thanks!

Lufenuron: Healing Chronic Fatigue & More

A month or so ago I was feeling “okay” but not great. Ever since I was given Levaquin antibiotics in the ER for food poisoning, about 4 years ago, I’ve had CFS/ME, brain fog, tinnitus, POTS, SIBO, food intolerance, asthma, ulcerative colitis, sinus and skin issues, depression/anxiety, rising blood sugar and constipation.

Does this sound familiar to any of you? What’s the common thread?

I’ve had fungal overgrowth, inside and out, for years, made much worse by broad spectrum antibiotics. Doctors shuffle me out of their offices when I ask for Nystatin powder, or other prescription antifungals, despite having obvious plaques on my scalp, feet, face, chest and groin, plus sinus and lung irritations consistent with candidiasis.

I have tried my best to control it with diet and herbals, like olive leaf, pau d’arco, grapefruit seed extract and berberine. It’s a chronic infection, so I’m slowly feeling worse and worse. Recently, even downing healthy amounts of cultured veggies and homemade kefir (both are powerful probiotics) hasn’t been very effective.

Flash back to a month ago, all it took was one starchy lunch that fed candida and i got horribly ill. I had GERD, muscle spasms, insomnia, asthma. In the days that followed, I knew I needed to do something more drastic to get the upper hand. Colloidal silver was helpful, but not something I wanted to take longer term. I heard about Lufenuron in an online forum. Not for human use, this chitin-inhibitor dissolves flea eggs, and… the outer shell of candida. Mammals don’t have chitin, so it’s apparently safe for dogs, cats and (theoretically) people.

It’s typically given for the first week of every month, daily, with a high fat meal (so it will deposit in tissues and be slow-released, rather than quickly leaving via the GI tract), then for the remaining 3 weeks of each month it goes to work destroying fungal overgrowth.

gorilla

Yes, humans aren’t supposed to use it, but there’s nothing stopping anyone from treating their gorilla, so that’s what I set out to do. Curiously, ever since i gave my pet ape pure Lufenuron, we both started to feel much better.

This is my record of that adventure, which will be updated periodically:

Day 1: dosage was 2 grams, and by the middle of Day 2, a major burst of mental clarity occurred. By that evening, the ability to sleep deeply had returned, to the point of waking on Day 3 — after 10 hours with no dreams, out like a light — and muscles felt much less sore, plus joint pain had disappeared.

To reiterate: during a 7 day total treatment “loading” window, 2 grams were administered daily, with a high-fat meal.

By Days 4 and 5, die-off symptoms emerged, which is not surprising, and lasted until Day 12: diarrhea, blurred vision, fatigue, insomnia and body aches. The good news: no more constipation, but it took 10 days for die-off to subside, and detoxing continues.

Day 13: colon inflammation is gone, and a healthy, sometimes ravenous appetite has emerged. I’m finding I don’t have to manipulate my neck as much to relieve POTS symptoms. I also think my tinnitus is a little better. It comes and goes, but I have more moments of silence.

Today, Day 14, upon waking, the gorilla is quite spunky, feeling like a randy teenager (Lufenuron might replace Viagra), and in the afternoon, muscles unwind in a characteristic activation of the parasympathetic nervous system, as nap time beckons. The vagal nerve is working now, which is intriguing! Was candida to blame for it running amok? It’s amazing how long, hot showers are enjoyable again (for my monkey). Relaxation is happening; anxiety is disappearing. There’s no more being stuck in fight-or-flight mode.

Healing like this is emotional, but “joy” hasn’t returned yet. My gorilla is still waiting for that.

By the way, people should not treat their primate’s flea problem with pure Lufenuron unless they’ve consulted a veterinarian, and should never treat themselves using medication not approved for humans. In fact, any and all new treatments contemplated should first be discussed with a physician. Please see the disclaimer.

With that said, CFS symptoms are improving, POTS also, along with so much more. Go, monkey, go.

To be continued.

UPDATE: I tried Lufenuron three times, and while the first dose provided incredible relief, when I took it again one month later it was only half as effective as it had initially been, and by the third dose, another month after that, it barely had an impact on my fungal overgrowth at all. This was despite mixing it with herbals.

Luckily I learned something valuable from the experiment: it seemed my immune system was the problem, so I began looking for something that could boost my body’s innate ability to fight candida. That led me to iodine, and a potential connection between fluorquinolone antibiotics, like Cipro and Levaquin, and hypothyroidism. Here’s the first installment of my iodine protocol. You’ll find the second article here. So far the results have been really encouraging, and unlike Lufenuron, iodine is both inexpensive and subject to much greater testing in humans.

If you enjoy this blog, you can support my work by buying things you need via this amazon portal HERE, or by purchasing any product linked in articles. It costs you nothing extra, and helps me continue writing. Thanks!

IBD and Vagal Nerve Issues: the Gut/Neck Axis?

Is it possible some of us with IBD also have an underlying neck injury, which drives gut inflammation?

The average human’s head is about the weight of a bowling ball, so it’s not surprising the neck can experience trauma due to an acute injury, or chronic misalignment through smart phone use (text-neck!) , poor posture on the job, inactivity, etc.

For me, inflammatory conditions began with antibiotic use, but they got MUCH WORSE after a neck injury, sustained in a traffic accident, several years ago. Initial symptoms were a stuffy, blocked nose without congestion, then asthma, sinusitis, tinnitus, TMJ, constipation, IBS, and a few years later ulcerative colitis.

UC lead to inactivity, more time spent in front of a computer, degenerative changes in my neck, throw in a dose of Levaquin for food poisoning, then SIBO, food intolerances, hyperadrenergic POTS, heart palpitations, GERD, panic attacks/anxiety, and finally chronic fatigue.

I’ve had quite a few breakthroughs with health in the last few years, but the most profound occurred about a week ago when I realized many of these symptoms I’ve had for years (while directly linked to antibiotics use) are also mediated by my posture, specifically, if my neck is in an unhealthy kyphotic curvature (reverse of normal alignment) or wonderful, yet illusive, lordosis .

What’s the inflammation connection? The vagal nerve runs throughout the body, getting its name “the wanderer” from the widespread path it travels, but it threads its way through a narrow channel in the cervical spine, such that compression of soft tissues between the upper cervical vertebrae can impair a lot of vagal function. This is my layperson’s view. Let’s see if our experience bears this out.

Given that the “fight or flight” response includes a clenching of neck muscles, in preparation for fleeing, is it possible this reduction of parasympathetic response (relaxation) is partially a built-in biomechanical feature of our bodies? If so, chronic stress, with its attendant tightening of that upper cervical spine, may be a vicious cycle — one that we can fairly easily monitor and turn around!

In a previous post I mentioned the posture pump I’ve been using. It’s fairly inexpensive, and definitely effective, but also impractical for anyone out and about in the world. What if we could do something similar with no equipment? Enter the “Alexander Technique“.

I’m warning you: this practice is so simple, you may wonder if you’re doing much at all, but when performed properly, you’ll notice a big difference. For some, this perfecting of posture and movement may be all you’ll need.

I have developed the habit, in just a few short days, of “sitting tall” in my car, as I’m driving. I tilt my head back ever so slightly, so that my chin is jutting forward. Lordosis! I can feel my nasal passages opening, my sinuses draining. I also notice my blood pressure dropping, as pressure (I assume) is taken off my vagal nerve.

Furthermore, when I adopt this posture throughout the day, I notice the “heat” that fills my entire lower abdomen, and gives rise to gut inflammation, mucus in stools, dull pain — this totally goes away. Hmmm…

I know I’m not the only person who experienced the sudden onset of hyperadrenergic POTS after a neck injury. A cardiologist I consulted a few years ago about my POTS symptoms mentioned one hyperadrenergic patient of his who was a perfectly healthy woman until she got whiplash in a car crash. I’m in touch with another woman via Facebook who had a skiing accident. She hurt her upper cervical spine, and has had POTS (standard, low blood pressure form) ever since.

This is certainly sad, especially given how little the allopathic doctors understand about hyperadrenergic POTS, or UC and other forms of IBD — typically they are good at treating acute symptoms — but if permanent neck trauma is indeed part of a multi-factoral range of inflammatory triggers, we can at least try to heal vagal nerve function from the gut side of the equation.

Our enteric nervous system is a feedback loop, so the Gut/Brain/(Neck?) Axis works in reverse, and if we have mechanical impairment “upstairs”, boosting gut flora signaling via the vagal nerve, from gut to brain, may compensate for the neurological impairment in some people. I’ve been tinkering a lot with eating gut bugs (in yogurt, sauerkraut, my own homemade kefir and probiotics) that may promote parasympathetic (relax and digest) activity. More on that in a future post.

Does anyone else have a history of neck injury or strain that could explain more global issues? If so, I’d appreciate hearing from you in the comments section.

EDIT: since writing this article not long ago, I’ve spoken to huge numbers of IBD sufferers who had a neck injury immediately preceding the onset of their illness. I’d appreciate your feedback. If you’ve had a similar experience and would like me to include your story in a future post, send me an email via the contact form. Thanks!